Mewgenics Guide
The ultimate Mewgenics guide with an interactive breeding calculator powered by exact genetics formulas, a house planner for all 1,258 furniture pieces, and in-depth class build guides. Master Mendelian inheritance, optimize your Stimulation values, and conquer every boss.
Tools & Databases
Interactive tools to help you play smarter.
Breeding Calculator
Calculate offspring probabilities with exact Stimulation formulas and trait inheritance.
Inbreeding Calculator
Assess inbreeding risk with Wright's COI formula and birth defect probability curves.
House Planner
Plan your house layout with all furniture pieces and real-time stat optimization.
Classes
Deep-dive into all 15 classes with skill trees, synergies, and recommended builds.
Items
Browse the complete item database with filters for slot, set bonuses, and item pools.
Bosses
Strategies for all 32 bosses including house invaders and hidden final bosses.
Tier List
Class and item tier rankings for the current meta.
Guides
In-depth guides on genetics, furniture optimization, and advanced combat tactics.
Popular
Most viewed pages right now.
Latest Guides
Expert strategy guides updated regularly.
Mewgenics All 32 Bosses Guide — Strategies, Unlock Conditions & Tips
Complete guide to all 32 Mewgenics bosses across 3 acts, house invasions & secret fights. Unlock conditions, HP values and winning strategies.
Mewgenics Cleric Guide — Best Builds, Skills & Strategies
Complete Mewgenics Cleric guide with 5 build archetypes, key skills, best passives, and gear recommendations for every playstyle.
Mewgenics Druid Guide — Builds, Skills & Best Synergies
Unlock and master the Druid in Mewgenics with optimal builds, terrain synergies, skill breakdowns, and team compositions for every act.
Mewgenics Fighter Guide — Best Builds, Skills & Combos
Master the Fighter class in Mewgenics with optimal builds, skill combos like Merciless + Zoomzerk, and boss-specific strategies.
Mewgenics Furniture Guide — House Stats, Best Layouts & Optimization
Optimize your Mewgenics house with 700+ furniture pieces. Learn the five house stats, adjacency bonuses, and best layouts for breeding.
Mewgenics Genetics Guide — Complete Breeding Formulas & Probabilities
Exact Mewgenics breeding formulas for stat inheritance, skill transfer, inbreeding coefficients, and body mutation mechanics.
About Mewgenics
| Developer | Edmund McMillen & Tyler Glaiel |
| Publisher | Edmund McMillen |
| Release Date | February 10, 2026 |
| Platforms | PC (Steam) |
| Genre | Tactical Turn-Based Roguelike |
| Rating | Metacritic: 90 |
Mewgenics is a tactical turn-based roguelike created by Edmund McMillen (The Binding of Isaac) and Tyler Glaiel. Released on February 10, 2026, it peaked at 115,428 concurrent Steam players — surpassing Hades 2 — and sold over one million copies in its first week. The game earned a Metacritic score of 90, cementing its place as one of the highest-rated indie releases of the year.
At its core, Mewgenics features a deep Mendelian genetics system where players breed cats with 79+ dominant and recessive traits, optimizing stats through Stimulation-driven probability formulas. With 15 classes ranging from Fighter to Jester, over 1,046 items, and 32 bosses (including hidden house invaders and multi-phase final encounters), the game offers hundreds of hours of strategic depth.
Our Mewgenics guide provides the tools the community needs most: an interactive breeding calculator with exact inheritance formulas reverse-engineered from the game code, a house planner covering all 700+ furniture pieces with adjacency bonuses, and comprehensive class guides for all 15 classes. Whether you're min-maxing your cattery or conquering The Rift, our data-driven tools give you the edge.